|Venue: Kingsholm Date: Saturday, 3 June Kick-off: 15:00 BST Coverage: Updates on BBC local radio and live scores on the BBC Sport website|
Gloucester make three changes as they try reach the Premiership semi-finals.
Scrum-half Ben Meehan and forwards Jack Singleton and Jordy Reid all return for the Cherry and Whites, who know they must beat Saracens and hope Northampton lose at home to Newcastle.
Saracens, already sure of a home semi-final, name an entirely changed 15 from the team that beat Northampton in their last match.
England’s Max Malins returns from a hamstring injury on the wing.
Duncan Taylor and Alex Lozowski start at centre, while Manu Vunipola is named as fly-half.
But England internationals Owen Farrell, Elliot Daly, Mako Vunipola, Maro Itoje, Nick Isiekwe, Jamie George and Billy Vunipola are all rested, as are the likes of Nick Tompkins, Aled Davies, Alex Goode and Vincent Koch.
Should Saracens win and Leicester lose at home to Wasps, they will top the Premiership.
They won the Championship last season after being relegated in 2020 due to salary cap rule breaches.
Gloucester: Carreras; Rees-Zammit, Harris, Kveseladze, Thorley; Hastings, Meehan; Rapava-Ruskin, Singleton, Gotovtsev, Clarke, Alemanno, Reid, Ludlow (capt), Ackermann
Replacements: Socino, Elrington, Balmain, Davidson, Clement, Chapman, Twelvetrees, May.
Saracens: Obatoyinbo; Malins, Lozowski, Taylor, Harris; Manu Vunipola, van Zyl; Mawi, Pifeleti, Clarey, Hunter-Hill, Swinson, Wray (capt), Knight, Venter
Replacements: Dan, Adams-Hale, Wainwright, Boon, Reffell, de Haas, Morris, Hallett
Referee: Wayne Barnes